With approximately 13.8 million minimally-invasive cosmetic surgeries performed in the United States, and approximately 12.2 million minimally invasive cosmetic treatments performed in 2011, most of these are undertaken in surgeons’ group practice or surgery center locations. The most common as well as the most dreaded complications are presented along with articles presenting “best practice for cosmetic surgery centers. Each topic presents Anesthesia, Infection control, Complication avoidance and management, along with technique video. Some of the topics include: Patient Selection in Outpatient Surgery; Airway Management in the Outpatient Setting; Deep Venous Thrombosis - Prevention and Management; Intravenous Sedation from the Surgeon’s Perspective; Postoperative Nausea and Vomiting; among other relevant issues to the surgeon. Guest Editors are Geoffrey Keyes and Robert Singer, both involved with the Association for Accreditation of Ambulatory Surgery and fervent about certified surgeons running ambulatory facilities for best outcomes and avoidance of mortalities and severe morbidities.